Introduction S&T&I FOR 2050: Science, Technology and Innovation for Ecosystem Performance – Accelerating Sustainability Transition ERA Industrial Technologies Roadmap on Human-Centric Research and Innovation Expectations and assumptions for the future in Horizon Europe New strategic alliance with Experience & Wiser IFI joins AMETIC, our president to lead the innovation commission International analysis on mission-oriented instruments Transformative governance of innovation ecosystems Action, agency, actionable: the semantics of innovation Fractal Innovation Towards smart circular economy; the role of digitalisation